There's a reason the people who could book any specialist in the country are getting on a plane instead. It isn't the price. It isn't the weather. And it isn't because they want another stem cell injection.
What these patients want is an entire regenerative protocol built around their body — developed by specialists who actually looked at what's wrong first.
Every other center treats the joint.
Our protocol treats the joint and the body it lives in.
Maybe you don't play as many rounds of golf. Maybe you've stopped skiing. Maybe you think twice about long flights. But none of it feels dramatic enough to change your life over — so you work around it. You adjust. And you tell yourself you're just getting older.
The one you work around without thinking about it anymore.
The one that quietly decides how many holes you'll actually play.
The one you've accepted as the cost of getting older.
They deserve the same level of attention you give everything else in your life. And right now, they're the only thing on your list you haven't actually handled.
Designed to identify what's actually causing the problem, treat the structures around it, and support your body's natural repair process.
Our specialists identify exactly what's driving the problem using high-definition ultrasound mapping — so every treatment is designed specifically for your body.
Ultrasound-guided MSC + PASC injections strengthen the joint, muscles, ligaments and surrounding structures. Cells go where the mapping says — the whole structure, not just the joint.
Next, a Therapeutic Plasma Exchange. Plasma is the liquid portion of your blood that carries the chemical messengers telling your body when to create inflammation. Removing those inflammatory proteins before treatment prepares your body to support healing.
Finally, a 100-million UC-MSC systemic infusion — umbilical cord-derived cells from RMI's own laboratory, collected after healthy births. They migrate toward inflamed and damaged tissue throughout the body, not just the joint you came in for.
Your plan is built by specialists inside a regenerative medicine institute with its own physicians, its own ISO-certified laboratory, and its own research team. The flagship clinic and laboratory sit together on Avenida Escazú in San José, Costa Rica, fully licensed in Costa Rica. Because this level of personalized care isn't widely available, patients travel from around the world to receive it.
Specialists who build the protocol — and stay accountable for it.
Cells are grown and verified twice — type, count, viability, safety — in RMI's own lab, not bought in.
A protocol built around your body, your history, and what you still want to do.
Everything here treats the body the joint lives in — systemic inflammation reduced, 100 million cells circulating, and the baselines to measure against next year.
Toxins, immune complexes, autoantibodies and inflammatory messengers are reduced along with the plasma that carries them.
Cells from RMI's own laboratory migrate toward inflamed and damaged tissue throughout the body.
Ultrasound maps every area to be treated, and cells go where the findings say — the whole structure, not just the joint.
Two baselines that make the year ahead measurable rather than remembered.
Concierge line — runs the whole trip
You book your flights. Everything from the moment you land is ours — fast-track customs, private transfers, and a room in the same building as the clinic.
Met on arrival in Costa Rica.
Same building as the clinic.
To and from SJO airport.
I can exercise the way I used to 15 years ago, which is pretty dramatic.
A NASA flight surgeon who spent decades keeping astronauts healthy has personally undergone RMI therapies — and has referred astronauts here.
Unscripted conversations with patients who travelled to Costa Rica, shared with their permission — not scripts, and not our words.
I was a competitive athlete. I've done some damage over the years … it's caused some joint damage.
The thing I noticed the most was probably my joints feeling less pain, less aches. They just felt stronger and cleaner and better.
On what changed after treatment.
One of my biggest regrets in life is the double knee replacement I went through about eight years ago.
On the surgery he had before he knew there was an alternative.
If you're looking at surgery for anything orthopedic — please don't. I'm telling you, from my own regrets.
I called and talked to 17 doctors and clinics around the world. So finding RMI was the beginning of the process that I circled back to after I did my research.
On how he vetted it.
To be able to move freely, without having to think about it on a day to day basis — to be pain free, to have the freedom to do that — just freed up my life in every area. Professionally, personally, spiritually.
I came out of that treatment and the next morning said, ‘Oh my God, I feel amazing.’ And they said, ‘No, Rudi, you don't feel amazing. You feel normal. And that's how we should all be feeling.’
I woke up the morning after my treatment, and I had absolutely zero pain in my spine … That was something that I've had for the last 25, 26 years.
I've had a lot of trouble with my ankle over the years, to the point where it's so painful I can hardly walk. And I live on a farm, so I need to be physically active.
My ankle doesn't collapse on me anymore. It's functional in a way that it wasn't. And I also know it still hurts and it's not perfect. … I think it's a great alternative to just automatically getting a hip replacement.
Against my better judgment, I decided to give in and have this lumbar spine surgery. I wake up and I'm in an ungodly amount of pain. I've never been the same since.
On the surgery that changed his life at 22.
There's definitively new tissue and a really massive reduction in the arthritis in the joint.
Comparing his imaging year over year.
Testimonial disclaimer — The stories on this page reflect the experience of individual patients and are presented with their consent. Testimonials are not a guarantee, promise, or prediction of any result. Individual outcomes vary widely based on diagnosis, overall health, and other factors, and no one should expect to experience the same outcome. The individuals featured have not been compensated for a specific claim of results.
Everything above — the mapping, the injections, the plasma exchange, the infusion, the baselines and the concierge line — in three nights in San José.
Most longevity and regenerative treatments are considered elective and are typically not covered by insurance. Eligibility is determined only after a full clinical review by a physician.
Our specialists continue monitoring your progress and guiding your recovery after you return home. The trip is the treatment — the relationship is what makes it work.
Treatment isn't right for everyone, and we'd rather tell you that early. Answer a few questions below and our team will review them before your consultation.
Prefer to start with a call? Speak to Samantha
Cunningham, Patient Specialist — she'll walk you through the mapping, the schedule
and the travel.
(346) 525-5151
DISCLAIMER — RMI Health is a longevity and regenerative medicine clinic that provides advanced, medically supervised stem cell and related therapies under license from the Costa Rican Ministry of Health. All treatments are subject to eligibility criteria and are only recommended after a full clinical review by qualified physicians, which may include medical history, diagnostic testing, and consultation with your existing care team. Outcomes vary between individuals and depend on many factors — including diagnosis, overall health, and adherence to medical guidance — so no specific result, degree of improvement, or duration of benefit can be promised or guaranteed. As with any medical procedure, regenerative and stem cell therapies carry potential risks, side effects, and limitations, which will be discussed with you in advance to support informed decision-making; RMI encourages patients to seek independent medical advice when needed and to consult insurers regarding coverage, as many longevity and regenerative treatments may be considered elective or investigational.
THIS NOTICE MUST BE PROVIDED TO YOU UNDER FLORIDA LAW — This centre performs one or more stem cell therapies that have not yet been approved by the United States Food and Drug Administration. You are encouraged to consult with your primary care provider before undergoing any stem cell therapy.
Nothing on this page is medical advice, a diagnosis, or a treatment recommendation, and it is not a substitute for consultation with a qualified healthcare provider. No physician-patient relationship is created by viewing this page or by submitting the form above.
Statements, reviews, testimonials, and depictions reflect the opinions, findings, or experiences of individual patients. These should not be interpreted as a guarantee, promise, or assurance of a particular outcome. Individual results vary.
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